Research Type: Medication Use

Analysis of multimorbidity, prescribed medication use and mortality over the Covid-19 pandemic period, with a specific focus on those with dementia – a longitudinal study of persons aged forty or more in 2011 in Northern Ireland

Older people are at high risk for Covid-19 and may have been impacted (and psychologically distressed) by the quarantine – entailing disconnection from family, community and usual health, social support and planned treatments. These may be amplified for people in rural areas where services are limited and both transport and digital-based communication services relatively poor. These issues may be more challenging for people living with dementia, generally associated with ageing, functional decline (Melis et al., 2013) and increased prescribing (Browne et al., 2017; Clague et al., 2017).

Read More »

The impact of the COVID-19 pandemic and quarantine on people with Severe Mental Illness (SMI) in Northern Ireland: an examination of prescribed psychotropic medication and mortality between Census 2011 and 2021

From March 2020 individuals, wider society and health care systems have all been seriously affected by the COVID-19 pandemic (WHO, 2020). It is likely that the pandemic has more severely impacted on people with prior mental health problems: generally research suggests that, pre-pandemic, people with Severe Mental Illness (SMI) (here we include schizophrenia, bi-polar disorder and major depressive disorder) could expect to experience considerable social exclusion, poor physical health and die up to 20 years earlier than the general population (Walker et al, 2015, NICE, 2018). They are also vulnerable to conditions such as diabetes (T2), cardiovascular disease (CVD), stroke and cancers, often due to lifestyle factors – poor diet, smoking, and lack of exercise (Lawrence et al, 2013). More generally the pandemic and subsequent lockdown may have exacerbated their physical and mental health. Many people with SMI either live alone or in shared community residential settings, and the closure of community-based rehabilitation centres during the pandemic, and absence of community activities, can exacerbate this sense of isolation and loneliness, leading potentially to mental health deterioration. Moreover, a reduction in services may limit access to routine health care including community and hospital psychiatric services.

Read More »
anxiolytic-antidepressant-n

pharmaco-epidemiological study of Anxiolytic and Antidepressant Drug uptake in Northern Ireland.

Recent epidemiological research highlights the importance of area factors on population health, with deprived areas having a greater proportion of physically and mentally ill inhabitants. One explanation is that these areas promote detrimental health behaviours, but increasingly the influence of individual characteristics are of interest. The social drift hypothesis suggests that individuals with poor health may migrate to particular areas, whilst selective migration suggests that the ‘healthy’ move out; collectively these effects can produce distributions of health that are erroneously suggestive of an area influence on mental health. In Northern Ireland mental ill health is increasingly becoming an issue.

Read More »
An exploratory analysis of the use of antibiotics by demographic and area characteristics – an exemplar study using the Northern Ireland Enhanced Prescribing Database (EPD) – NILS Distinct Linkage Project.

An exploratory analysis of the use of antibiotics by demographic and area characteristics – an exemplar study using the Northern Ireland Enhanced Prescribing Database (EPD) – NILS Distinct Linkage Project.

The EPD is an integrated patient-centred electronic record of all drugs prescribed by General Practitioners in Northern Ireland. Using the EPES database this project will analyse antibiotic prescribing patterns for the 12 months ending May 2010. It will examine variations in use of antibiotics by individual socio-demographic characteristics and area characteristics, to help to inform the management of antibiotics prescribing in Northern Ireland.

Read More »